Updated 4 h ago · first seen 11 Sept 2026
paper_01M294FPV62GCH1MA386GHAECF
- Published
- 11 Sept 2026
- T1 · 4 h ago
- arXiv
- 2609.10644
- T1 · 4 h ago
- Category
- q-bio.BM
- T1 · 4 h ago
Abstract
Computational RNA structure pipelines generate many candidate conformations for the same sequence. Reliable evaluation therefore requires more than recognising plausible geometry, it requires determining whether that geometry is compatible with the sequence. We introduce SIRGE, a sequence-informed geometric evaluator that conditions structural representations on nucleotide embeddings from a pretrained RNA language model. Early results show that SIRGE outperforms established evaluators in Kendall--$\tau$ alignment, Top-1 selection, and Top-3 ranking. Controlled comparisons further show that sequence conditioning corrects errors made by an otherwise matched geometric model and improves target-level rank structure. These findings provide initial evidence that pretrained sequence representations supply ranking information that complements geometric reasoning.
Authors 8
Andrea Zerio, Yighua Yao, Alessandro Micheli, Roland G. Huber, Mile Sikic, Samir Bhatt, Andres R. Masegosa, Yuangang Pan
Specification
- Official page
Source:arXiv (Atom API + RSS)T1observed 4 h agohigh
- Arxiv announce type
- cross
Source:arXiv (Atom API + RSS)T1observed 4 h agohigh
- arXiv id
- 2609.10644
Source:arXiv (Atom API + RSS)T1observed 4 h agohigh
- Categories
- q-bio.BM, cs.LG
Source:arXiv (Atom API + RSS)T1observed 4 h agohigh
Source:arXiv (Atom API + RSS)T1observed 4 h agohigh
- Primary category
- q-bio.BM
Source:arXiv (Atom API + RSS)T1observed 4 h agohigh
- Published
- 11 Sept 2026
Source:arXiv (Atom API + RSS)T1observed 4 h agohigh
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Provenance
Attributed facts
9
Source tiers
T19
Freshest observation
4 h ago
Conflicts
None
No models linked to this paper yet.
- Authors
- Andrea Zerio, Yighua Yao, Alessandro Micheli
As of
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Claim history · Authors
Claims are temporal and append-only: a new observation closes the previous claim (valid_to) instead of overwriting it. Conflicting claims from different sources are kept side by side and flagged — never averaged. Methodology →
New paper: Sequence-Informed Geometric Evaluation of RNA 3D Structures
arxiv
| Source | Document | Type | Tier | Last observed | Snapshots |
|---|---|---|---|---|---|
| arXiv (Atom API + RSS) | rss.arxiv.org/rss/cs.LG | feed | T1· Official | 2 h ago | 1 |
Tier 1 = official/primary, 2 = quality secondary, 3 = community, 4 = unverified. Every snapshot is archived; see all sources and the methodology.