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SCINTILLA-SNN: A Spiking Multi-Scale Selective Aggregation Network for Perineural Invasion Prediction

arxiv.org/abs/2609.11237

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Updated 5 h ago · first seen 11 Sept 2026

paper_01M294H1XHX8X06M55C9HTA8GC

Published
11 Sept 2026
T1 · 5 h ago
arXiv
2609.11237
T1 · 5 h ago
Category
cs.CV
T1 · 5 h ago

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9 claims · 9 properties

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https://arxiv.org/abs/2609.11237currentcurrentarXiv (Atom API + RSS)T1highdeterministic

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Preoperative prediction of perineural invasion (PNI) in cholangiocarcinoma (CCA) is clinically valuable but remains challenging because PNI-related cues on magnetic resonance imaging (MRI) are subtle, sparse, and spatially localized around the tumor boundary. Standard 3D CNN and transformer architectures process volumetric data in a dense or spatially uniform manner, which can dilute subtle PNI-related evidence while requiring a large number of multiply-accumulate operations over 3D feature grids. To address these limitations, we propose SCINTILLA-SNN, a 3D spiking network composed of a four-stage hierarchical backbone and a Multi-Scale Spike Aggregation (MSSA) module for PNI prediction. The backbone extracts hierarchical volumetric representations through spiking convolutional stages and local spike window modulation stages. Given the resulting stage-wise representations, MSSA maps each spatial token to a learnable content value and modulates it with a spike-dynamics gate derived from firing rate and timestep-wise membrane-potential variability. The resulting score, referred to as the diagnostic token score, is used to selectively aggregate sparse PNI-related evidence. Experiments on a 10-year retrospective cohort of 182 CCA patients show that SCINTILLA-SNN achieves an AUROC of 0.748 under 5-fold cross-validation, while reducing the estimated inference energy by 23.18$\times$ compared with dense MAC-only computation of the same network.currentcurrentarXiv (Atom API + RSS)T1highdeterministic

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newcurrentcurrentarXiv (Atom API + RSS)T1highdeterministic

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2609.11237currentcurrentarXiv (Atom API + RSS)T1highdeterministic

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Youngung Han, Yului Jeong, Kyeonghun Kim, Dohyun Kweon, Suah Park, Hyunsu Go, Sungha Park, Anna Jung, Jinyong Jun, Yunho Choe, Yunjin Seo, Ken Ying-Kai Liao, Hyuk-Jae Lee, Nam-Joon KimcurrentcurrentarXiv (Atom API + RSS)T1highdeterministic

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cs.CVcurrentcurrentarXiv (Atom API + RSS)T1highdeterministic

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https://arxiv.org/pdf/2609.11237currentcurrentarXiv (Atom API + RSS)T1highdeterministic

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cs.CVcurrentcurrentarXiv (Atom API + RSS)T1highdeterministic

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11 Sept 2026currentcurrentarXiv (Atom API + RSS)T1highdeterministic

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