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SCINTILLA-SNN: A Spiking Multi-Scale Selective Aggregation Network for Perineural Invasion Prediction

arxiv.org/abs/2609.11237

Updated 51 min ago · first seen 11 Sept 2026

paper_01M294H1XHX8X06M55C9HTA8GC

Published
11 Sept 2026
T1 · 51 min ago
arXiv
2609.11237
T1 · 51 min ago
Category
cs.CV
T1 · 51 min ago

Abstract

Preoperative prediction of perineural invasion (PNI) in cholangiocarcinoma (CCA) is clinically valuable but remains challenging because PNI-related cues on magnetic resonance imaging (MRI) are subtle, sparse, and spatially localized around the tumor boundary. Standard 3D CNN and transformer architectures process volumetric data in a dense or spatially uniform manner, which can dilute subtle PNI-related evidence while requiring a large number of multiply-accumulate operations over 3D feature grids. To address these limitations, we propose SCINTILLA-SNN, a 3D spiking network composed of a four-stage hierarchical backbone and a Multi-Scale Spike Aggregation (MSSA) module for PNI prediction. The backbone extracts hierarchical volumetric representations through spiking convolutional stages and local spike window modulation stages. Given the resulting stage-wise representations, MSSA maps each spatial token to a learnable content value and modulates it with a spike-dynamics gate derived from firing rate and timestep-wise membrane-potential variability. The resulting score, referred to as the diagnostic token score, is used to selectively aggregate sparse PNI-related evidence. Experiments on a 10-year retrospective cohort of 182 CCA patients show that SCINTILLA-SNN achieves an AUROC of 0.748 under 5-fold cross-validation, while reducing the estimated inference energy by 23.18$\times$ compared with dense MAC-only computation of the same network.

Authors 14

Youngung Han, Yului Jeong, Kyeonghun Kim, Dohyun Kweon, Suah Park, Hyunsu Go, Sungha Park, Anna Jung, Jinyong Jun, Yunho Choe, Yunjin Seo, Ken Ying-Kai Liao, Hyuk-Jae Lee, Nam-Joon Kim

Specification

Official page

Source:arXiv (Atom API + RSS)T1observed 51 min agohigh

Arxiv announce type
new

Source:arXiv (Atom API + RSS)T1observed 51 min agohigh

arXiv id
2609.11237

Source:arXiv (Atom API + RSS)T1observed 51 min agohigh

Categories
cs.CV

Source:arXiv (Atom API + RSS)T1observed 51 min agohigh

PDF

Source:arXiv (Atom API + RSS)T1observed 51 min agohigh

Primary category
cs.CV

Source:arXiv (Atom API + RSS)T1observed 51 min agohigh

Published
11 Sept 2026

Source:arXiv (Atom API + RSS)T1observed 51 min agohigh

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Provenance

Attributed facts

9

Source tiers

T19

Freshest observation

51 min ago

Conflicts

None