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Four Generations of Quantum Biomedical Sensors

arxiv.org/abs/2603.29944

quality89

Updated 2 h ago · first seen 12 Sept 2026

paper_01M29X358JF30HDH3SZYVH8DCB

Published
12 Sept 2026
T1 · 2 h ago
arXiv
2603.29944
T1 · 2 h ago
Category
quant-ph
T1 · 2 h ago

Abstract

-cross Abstract: Quantum sensing technologies offer transformative potential for ultra-sensitive biomedical sensing, yet their clinical translation remains constrained by classical noise limits and a reliance on macroscopic ensembles. We propose a unifying generational framework to organize the evolving landscape of quantum biosensors based on their utilization of quantum resources. First-generation devices utilize discrete energy levels for signal transduction but follow classical scaling laws. Second-generation sensors exploit quantum coherence, extending precision with the coherence time up to the standard quantum limit, while third-generation architectures employ entanglement and spin squeezing to approach Heisenberg-limited precision. We define an emerging fourth generation characterized by the end-to-end integration of quantum sensing with quantum learning and variational circuits, enabling adaptive inference directly within the quantum domain. By introducing a bandwidth-matching analysis pairing the neural signal hierarchy with platform response bandwidths, classifying deployed clinical devices by precision-scaling class and sensor-tissue proximity, and outlining a staged physical-milestone roadmap toward learning-integrated sensor networks, we identify key technological bottlenecks and chart the transition from measuring physical observables to extracting structured biological information with quantum-enhanced intelligence.

Authors 10

Jonathan Beaumariage, Junyu Liu, Kang Kim, Kaushik Seshadreesan, M. V. Gurudev Dutt, Priyam Srivastava, Ronghe Wang, Tom Purdy, Xin Jin, Yuqing Li

Specification

Official page

Source:arXiv (Atom API + RSS)T1observed 2 h agohigh

Arxiv announce type
replace

Source:arXiv (Atom API + RSS)T1observed 2 h agohigh

arXiv id
2603.29944

Source:arXiv (Atom API + RSS)T1observed 2 h agohigh

Categories
cs.AI, quant-ph

Source:arXiv (Atom API + RSS)T1observed 2 h agohigh

PDF

Source:arXiv (Atom API + RSS)T1observed 2 h agohigh

Primary category
quant-ph

Source:arXiv (Atom API + RSS)T1observed 2 h agohigh

Published
12 Sept 2026

Source:arXiv (Atom API + RSS)T1observed 2 h agohigh

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Provenance

Attributed facts

9

Source tiers

T19

Freshest observation

2 h ago

Conflicts

None