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Two-Parameter Flow Map Learning for Continuous-Time Diffeomorphic Image Registration

arxiv.org/abs/2609.10789

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Updated 2 h ago · first seen 11 Sept 2026

paper_01M294H1P319MV3A2ETDZT84BM

Published
11 Sept 2026
T1 · 2 h ago
arXiv
2609.10789
T1 · 2 h ago
Category
cs.CV
T1 · 2 h ago

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Abstractabstract1

Claim history for Abstract
ValueValid from → toStatusSourceConfidenceExtractor
Diffeomorphic image registration is central to medical image analysis, enabling anatomically consistent alignment across subjects. Most learning-based diffeomorphic methods model autonomous ODEs(ordinary differential equations) by parameterizing a stationary velocity field and recovering deformations via scaling-and-squaring. While non-autonomous ODEs with time-dependent velocities increase expressiveness, existing approaches rely on numerical integration to implicitly enforce flow structure that entangles model expressiveness with discretization accuracy. We propose a framework to directly learn the continuous-time solution of a non-autonomous ODE formulated as a two-parameterflow map. By enforcing cocycle consistency, a fundamental structural property of time-varying flows, we learn the flow maps without time discretization and velocity integration during training. The framework recovers diffeomorphic mappings at inference using a small number of compositions. Our proposed framework seamlessly incorporates standard registration backbones and improves alignment accuracy consistently across nine datasets while preserving diffeomorphic structure. Notably, the proposed method achieves an average Dice improvement of 2.1% on brain MRI benchmarks, a 12% TRE reduction on lung CT, and a 2.6% Dice gain on cardiac MRI and ultrasound datasets.currentcurrentarXiv (Atom API + RSS)T1highdeterministic

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