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MedGEN-Bench: A Contextually Entangled Benchmark for Open-ended Multimodal Medical Generation

arxiv.org/abs/2511.13135

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Updated 5 h ago · first seen 11 Sept 2026

paper_01M294H31M65DG1T4D5JFYC91C

Published
11 Sept 2026
T1 · 5 h ago
arXiv
2511.13135
T1 · 5 h ago
Category
cs.CV
T1 · 5 h ago

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https://arxiv.org/abs/2511.13135currentcurrentarXiv (Atom API + RSS)T1highdeterministic

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Medical vision-language models (VLMs) are increasingly expected to support clinical workflows through diagnostic text and relevant medical images. However, current medical visual benchmarks have three recurring limitations: query-image misalignment from queries weakly grounded in specific image instances, closed-ended formats that narrow answer space and encourage shortcut-based prediction, and text-centric output paradigms that limit evaluation of image-generation and image-editing capabilities. We introduce MedGEN-Bench, a benchmark for open-ended multimodal medical generation. The evaluation snapshot reported in this manuscript comprises 6,422 image-text pairs reviewed by clinical experts and models, spanning 6 canonical imaging modalities, 15 clinical tasks, and 27 named subtasks. It includes 1,100 Visual Question Answering (VQA) pairs, 3,872 Image Editing pairs, and 1,450 Contextual Multimodal Generation pairs. MedGEN-Bench centers on contextual entanglement: dependence of an instruction's intended output on the particular image instance rather than on task wording alone. The benchmark operationalizes this concept through image-grounded instructions and extends evaluation to open-ended multimodal outputs. Its tiered evaluation protocol combines reproducible reference-based fidelity and similarity measures with a structured, checklist-guided assessment by a medical VLM judge. We evaluate 10 compositional frameworks, 2 dedicated image-editing models, 3 unified models, and 5 VLMs. The results show image-output tasks remain unsaturated. Contextual augmentation increases mean image-instruction similarity from 0.273 to 0.372, while a 1,000-case medical-expert audit shows moderate agreement between judge scores and clinician ratings. Source code and dataset are available at https://yangjj007.github.io/medgen.currentcurrentarXiv (Atom API + RSS)T1highdeterministic

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replacecurrentcurrentarXiv (Atom API + RSS)T1highdeterministic

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2511.13135currentcurrentarXiv (Atom API + RSS)T1highdeterministic

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Junjie Yang, Yuhao Yan, Gang Wu, Rui Qian, Zhisheng Chen, Haijiang Li, Yuhe Wu, Qichao Zhao, Dawen Tian, Xiang Wan, Fenglei Fan, Wenjian Qin, Yongquan Zhang, Feiwei Qin, Changmiao WangcurrentcurrentarXiv (Atom API + RSS)T1highdeterministic

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cs.CVcurrentcurrentarXiv (Atom API + RSS)T1highdeterministic

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https://arxiv.org/pdf/2511.13135currentcurrentarXiv (Atom API + RSS)T1highdeterministic

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cs.CVcurrentcurrentarXiv (Atom API + RSS)T1highdeterministic

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11 Sept 2026currentcurrentarXiv (Atom API + RSS)T1highdeterministic

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