Cross-Lingual Clinical Annotation Projection as Constrained Text Generation: A Six-Language Study — Paper

Abstract

Background: To determine whether cross-lingual clinical annotation projection can be formulated as a text-preserving, document-level generative task that produces verifiable character-level annotations for multilingual clinical corpus construction, and to characterize its robustness and computational trade-offs relative to candidate-based projection pipelines. Methods: We developed a constrained LLM projection workflow that inserts entity tags directly into immutable target-language text, followed by deterministic validation and character-offset reconstruction. We evaluated it alongside supervised candidate-span projection and hybrid ML-LLM refinement for transferring Spanish Disease, Symptom, and Procedure annotations into six languages. Evaluation used MultiClinAI gold standard with strict span matching and character-overlap F1 Results: Direct LLM projection achieved the strongest and most consistent performance. GLM 5.2 obtained a mean Strict F1 of 0.9201 across 18 language-entity combinations, while locally deployable Gemma4:31B achieved 0.9133. The best LLM configuration improved Strict F1 over the previous state of the art in all 18 settings, by 0.0564-0.1512, yielding 55,416 grounded mentions with reconstructed offsets. Conclusions: Direct LLM-based projection enables high-quality multilingual clinical annotation transfer and provides a practical approach for extending clinical NLP resources to languages with fewer annotated datasets and language-specific tools. Combined with local inference and deterministic validation, it can substantially reduce expert time and cost for multilingual clinical corpus construction.

Authors 3

\'Alvaro Rey-Blanes, Francisco J. Moreno-Barea, Francisco J. Veredas

Specification

Official page: arxiv.org/abs/2609.11450
Source:arXiv (Atom API + RSS)T1observed 5 h agohigh
Arxiv announce type: new
Source:arXiv (Atom API + RSS)T1observed 5 h agohigh
arXiv id: 2609.11450
Source:arXiv (Atom API + RSS)T1observed 5 h agohigh
Categories: cs.CL, cs.AI
Source:arXiv (Atom API + RSS)T1observed 5 h agohigh
PDF: arxiv.org/pdf/2609.11450
Source:arXiv (Atom API + RSS)T1observed 5 h agohigh
Primary category: cs.CL
Source:arXiv (Atom API + RSS)T1observed 5 h agohigh
Published: 11 Sept 2026
Source:arXiv (Atom API + RSS)T1observed 5 h agohigh

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T19

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5 h ago

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Authors: \'Alvaro Rey-Blanes, Francisco J. Moreno-Barea, Francisco J. Veredas

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Value	Valid from → to	Status	Source	Confidence	Extractor
cs.CL, cs.AI	11 Sept 2026 21:03 UTC → current	current	arXiv (Atom API + RSS)T1	high	deterministic

Claims are temporal and append-only: a new observation closes the previous claim (valid_to) instead of overwriting it. Conflicting claims from different sources are kept side by side and flagged — never averaged. Methodology →

11 Sept 2026
New paperPaperCross-Lingual Clinical Annotation Projection as Constrained Text Generation: A Six-Language Study
New paper: Cross-Lingual Clinical Annotation Projection as Constrained Text Generation: A Six-Language Study
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Source	Document	Type	Tier	Last observed	Snapshots
arXiv (Atom API + RSS)	rss.arxiv.org/rss/cs.CL	feed	T1· Official	4 h ago	1

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